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Year : 2019  |  Volume : 12  |  Issue : 6  |  Page : 544-546

Giant pulmonary hamartoma with foci of placental transmogrification of the lung

Dr. D.Y. Patil Medical College Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth, Pune, Maharashtra, India

Correspondence Address:
Namrata Patro
B-49, Old Girls Hostel, Dr. D.Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune - 411 018, Maharashtra
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mjdrdypu.mjdrdypu_245_18

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Pulmonary hamartoma is the most common benign tumor of lung which is composed of mesenchymal tissues and entrapped respiratory epithelium. The size usually varies between 1 and 5 cm, and it commonly occurs in the sixth and seventh decade, with only 6% of cases seen under the age of 30 years with male preponderance. These lesions are indicative of an abnormal proliferation and mixing of the normal components present in the lung tissue. “Placental transmogrification of the lung” is an extremely rare disease entity, with only <30 cases documented till date. The etiology and pathogenesis still remain unclear. Placental transmogrification is a condition where the alveoli resemble the chorionic villi of placenta. This case is presented to highlight the unusual large size (21.5 cm × 18 cm × 11 cm) of pulmonary hamartoma in a young female (32 years) showing areas of placental transmogrification on microscopy. Awareness of this rare entity will help in making definitive diagnosis.

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