Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Print this page Email this page Users Online: 234
Year : 2021  |  Volume : 14  |  Issue : 3  |  Page : 292-296

A clinico-hematological evaluation of pancytopenia at government medical college and hospital, latur: A 2-year observational study

1 Department of Pathology, Government Medical College, Latur, Maharashtra, India
2 Department of Pathology, Government Medical College, Jalgaon, Maharashtra, India

Correspondence Address:
Rahul Pundalik Jadhav
Flat No. 5, Chandrashil Apartment, Behind Kashi Vishweshwar Temple, New Bhagwan Nagar, Jalgaon, Maharashtra
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mjdrdypu.mjdrdypu_333_19

Rights and Permissions

Context: Pancytopenia is defined by reduction of all the three formed elements of blood below the normal reference. Hematological investigation forms the bedrock in the management of patients with pancytopenia and therefore needs detailed study. The aim of this study was to identify the underlying etiologies of pancytopenia cases presenting at our institute with clinico-hematological evaluation. Materials and Methods: In this 2-year prospective study, 105 patients aged ≥15 years admitted in hospital with a hematological diagnosis of pancytopenia followed by bone marrow aspiration and/or biopsy after receiving an informed consent were studied. The criteria applied for pancytopenia were hemoglobin level: <13.5 g/dL for males and <11.5 g/dL for females; total leukocyte count: <4 × 109/L; and platelet count: <150 × 109/L. Pregnant women and patients aged <15 years along with those who did not give consent for bone marrow aspiration or biopsy were excluded. A detailed clinical examination was carried out in all cases. Results: In the present study, megaloblastic anemia (67.62%) was the most common cause of pancytopenia, followed by aplastic anemia (15.25%), leukemia (3.81%), malaria (3.81%), hypersplenism (3.81%), liver cirrhosis (1.90%), myelofibrosis (1.90%), multiple myeloma (1%), and enteric fever (1%). Conclusions: The severity of pancytopenia and the underlying pathology determine the management and prognosis. Thus, comprehensive clinical and hematological evaluation of pancytopenia cases will help in identification of the correct cause and in implementing the appropriate therapy.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded54    
    Comments [Add]    

Recommend this journal