Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Print this page Email this page Users Online: 2656

Ahead of print publication  

Laboratory screening technique for filariasis in tropical endemic area: Thick smear versus buffy coat capillary tube versus low-concentration normal saline technique: A cost analysis

1 KMT Center, Bangkok, Thailand
2 Department of Community Medicine, Dr DY Patil University; Research Center, Parasitic Disease Research Unit, Suranaree University of Technology, Nakhon Ratchasima, Thailand Pune, Maharashtra, India

Date of Submission30-Mar-2021
Date of Decision30-Apr-2021
Date of Acceptance28-May-2021

Correspondence Address:
Sora Yasri,
KMT Center, Bangkok
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mjdrdypu.mjdrdypu_236_21

How to cite this URL:
Yasri S, Wiwanitkit V. Laboratory screening technique for filariasis in tropical endemic area: Thick smear versus buffy coat capillary tube versus low-concentration normal saline technique: A cost analysis. Med J DY Patil Vidyapeeth [Epub ahead of print] [cited 2022 Dec 6]. Available from: https://www.mjdrdypv.org/preprintarticle.asp?id=345907

Dear Sir,

Lymphatic filariasis is an important tropical disease. For disease control, screening by laboratory technique plays an important role. The blood test is routinely used for screening for microfilarial parasites.[1] There are many alternative laboratory techniques for screening. The different techniques might provide different diagnostic properties and result in different epidemiological records; hence, standardization is needed.[2] In addition, it is necessary to analyze on cost for planning for implementation of a laboratory technique.

Here, the authors performed a reappraise on the data of filariasis screening from an endemic tropical area, Myanmar–Thailand border area (GPS location 13.392118426381861, 99.5372683229726). The three alternative studied techniques are (a) thick smear, (b) buffy coat capillary tube, and (c) low-concentration normal saline techniques. The primary data are from the previous study on the diagnostic property, detection rate, of the three techniques,[3] and the data on local cost in USD. The cost–utility analysis is done and the results are shown in [Table 1]. It seems that the cost of low-concentration normal saline technique is the lowest. From incremental cost analysis, low-concentration normal saline technique has an incremental cost per utility comparing to thick smear and buffy coat capillary tube equal to 0.35 and 0.25 USD, respectively.
Table 1: Comparison of laboratory screening technique for filariasis in tropical endemic area

Click here to view

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Mathison BA, Couturier MR, Pritt BS. Diagnostic identification and differentiation of microfilariae. J Clin Microbiol 2019;57:e00706-19.  Back to cited text no. 1
Vinkeles Melchers NV, Coffeng LE, de Vlas SJ, Stolk WA. Standardisation of lymphatic filariasis microfilaraemia prevalence estimates based on different diagnostic methods: A systematic review and meta-analysis. Parasit Vectors 2020;13:302.  Back to cited text no. 2
Taokaew K, Pipatsatitpong D. Evaluation of low concentration normal saline technique for microfilaria detection in migrant workers at Pak Tho Hospital, Ratchaburi Province. J Med Tech Assoc Thailand 2018;46:466578-88.  Back to cited text no. 3


  [Table 1]


     Search Pubmed for
    -  Yasri S
    -  Wiwanitkit V
    Access Statistics
    Email Alert *
    Add to My List *
* Registration required (free)  

  In this article
   Article Tables

 Article Access Statistics
    PDF Downloaded8    

Recommend this journal