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Comparative study of lipid profile among young smokers and nonsmokers in south Indian population

1 Department of Gastroenterology, M. S. Ramaiah Hospitals, Bengaluru, Karnataka, India
2 Department of General Medicine, M. S. Ramaiah Hospitals, Bengaluru, Karnataka, India, Bengaluru

Correspondence Address:
Srikanth Narayanaswamy,
Department of General Medicine, M. S. Ramaiah Hospitals, Bengaluru-560 054, Karnataka
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/mjdrdypu.mjdrdypu_873_21

Background: In India, the predominant way of tobacco consumption is by smoking cigarettes, which is a vital risk factor for atherosclerotic vascular disease, which in turn is affected by abnormality in the lipid profile. Aim: To evaluate the alteration in the serum lipid profile between young smokers and nonsmokers. Materials and methods: The study included a total of 148 participants, who were divided into light (n = 25), moderate (n = 25), heavy (n = 24) smokers ("S" group), and nonsmokers ("NS" group, n = 74). Along with demographic data, blood samples were collected after overnight fasting under aseptic conditions. The samples were centrifuged and the lipid profile estimation of substances including serum cholesterol, triglycerides, high-density lipoprotein cholesterol, low- and very low-density lipoprotein cholesterol were performed. Independent sample t test and one-way analysis of variance were employed for statistical analysis, considering P ≤.05 as significant. Results: The mean years of smoking were 7.91 ± 4.67 years and average cigarettes smoked per day were 13.43 ± 6.66. The inter-group difference in the lipid profiles were significant (P <.001). An increasing trend of mean cholesterol, low-density lipoprotein cholesterol, triglycerides, and very low-density lipoprotein cholesterol with regard to lower to higher smoking index, while high-density lipoprotein cholesterol levels significantly showed decreasing trend with regard to lower to higher smoking index (P <.001). Conclusion: The present study reported abnormal lipid level in smokers in comparison to the nonsmokers, with the amount and duration of smoking also influencing dyslipidemia.

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