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  Indian J Med Microbiol
 

Figure 3: Photomicrography of some important diagnoses. (1) Lupus Vulgaris. (1a) ×4 showing full thickness epidermis with the dermis and subcutaneous layer where epidermal changes with dermal infiltrates are seen. (1b) ×10 showing hyperplastic acanthotic epidermis with dense dermal inflammatory infiltrate. (1c) ×40 shows dermal inflammatory infiltrate composed of epithelioid cells forming granuloma. (2) Borderline tuberculoid leprosy. (2a) ×4 shows presence of epidermis showing no changes and dermis with dense inflammatory infiltrate. (2b) ×10 showing dense dermal infiltrate with epithelioid granuloma. (2c) ×40 showing well-formed epithelioid granuloma composed of macrophages and lymphoid cells. (3) Lepromatous Leprae. (3a) ×10 showing epidermis separated from dermis by grenz zone. (3b) ×40 showing lymphohistocytes collection with some macrophages having foamy changes

Figure 3: Photomicrography of some important diagnoses. (1) Lupus Vulgaris. (1a) ×4 showing full thickness epidermis with the dermis and subcutaneous layer where epidermal changes with dermal infiltrates are seen. (1b) ×10 showing hyperplastic acanthotic epidermis with dense dermal inflammatory infiltrate. (1c) ×40 shows dermal inflammatory infiltrate composed of epithelioid cells forming granuloma. (2) Borderline tuberculoid leprosy. (2a) ×4 shows presence of epidermis showing no changes and dermis with dense inflammatory infiltrate. (2b) ×10 showing dense dermal infiltrate with epithelioid granuloma. (2c) ×40 showing well-formed epithelioid granuloma composed of macrophages and lymphoid cells. (3) Lepromatous Leprae. (3a) ×10 showing epidermis separated from dermis by grenz zone. (3b) ×40 showing lymphohistocytes collection with some macrophages having foamy changes